Abstract Identifying effective drug targets, with little or no side effects, remains an ever challenging task.A potential pitfall of failing to uncover the correct drug targets, due to side effect of pleiotropic genes, might lead the potential drugs to be illicit and withdrawn.Simplifying disease complexity, for the investigation of the mechanistic
Cultivated meat, also known as cell-based or clean meat, utilizes mesenchymal stem cells to cultivate mature cell types like adipocytes, which are pivotal for imparting the desired taste and texture.The delivery of differentiated cells, crucial in cultivated meat production, is facilitated through extensive exploration of 3D culturing techniques mi
Lung epithelial and endothelial cell death accompanied by inflammation contributes to hyperoxia-induced acute lung injury (ALI).Impaired resolution of ALI can promote and/or perpetuate lung pathogenesis, including fibrosis.Previously, we have shown Inner Door Glass seal that the transcription factor Nrf2 induces cytoprotective gene expression and c
The british legal philosopher John Austin stands at the threshold of the evolution of the legal positivist tradition.His work, which dates back to the first half of the 19th century, was especially important to establish the basic elements of this school of legal understanding.Among his contributions to the legal positivist doctrine, lies the creat